Modified associative learning T-maze test for zebrafish (Danio rerio) and other small teleost fish

Resultado de la investigación: Chapter

20 Citas (Scopus)


Associative learning is a form of classical (Pavlovian) conditioning in which a neutral stimulus (e.g., the color green) is paired with a stimulus of some significance to an animal (e.g., food), such that for the animal, the color becomes synonymous with food to evoke the same innate, reflexive behavioral responses (e.g., food seeking). This protocol is designed to test the acquisition and extinction of reward-visual stimulus association in zebrafish (Danio rerio) in a T-maze. It is based on the visual discrimination protocol of Colwill et al. (2005), in which colors or patterns are paired with a food reward. The protocol has been modified to include a reward box within the T-maze aquarium so that the influence of drug reinforcement can be studied without the potential confound of reward residues contaminating the testing arena.

Idioma originalEnglish (US)
Título de la publicación alojadaZebrafish Neurobehavioral Protocols
EditoresAllan Kalueff, Jonathan Cachat
Número de páginas13
EstadoPublished - ene 1 2011

Serie de la publicación

ISSN (versión impresa)0893-2336
ISSN (versión digital)1940-6045

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Psychiatry and Mental health


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