Modeling glucose kinetics in vivo in the human forearm. Rationale and a dual tracer study

M. P. Saccomani, C. Cobelli, A. Gabana, E. Ferrannini, R. Bonadonna, R. A. Gelfand, R. A. De Fronzo

Resultado de la investigación: Conference articlerevisión exhaustiva

Resumen

In vivo evaluation in humans of transport and metabolism of substrates in skeletal muscle of the forearm is important but difficult. Available approaches are briefly reviewed. In this paper we first outline a general modeling strategy to address this issue in the context of multiple tracer experiment design. A partly-flow compartmental model to assess the kinetics of glucose transport from a dual-tracer study is then presented. The effect of insulin is examined.

Idioma originalEnglish (US)
Páginas (desde-hasta)345-350
Número de páginas6
PublicaciónIFAC Proceedings Series
N.º1
EstadoPublished - dic 1 1989
Publicado de forma externa
EventoIFAC Symposium on Modelling and Control in Biomedical Systems - Venice, Italy
Duración: abr 6 1988abr 8 1988

ASJC Scopus subject areas

  • Engineering(all)

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