Microtubules and axon regeneration in C. elegans

Producción científica: Review articlerevisión exhaustiva

3 Citas (Scopus)

Resumen

Axon regeneration is a fundamental and conserved process that allows the nervous system to repair circuits after trauma. Due to its conserved genome, transparent body, and relatively simple neuroanatomy, C. elegans has become a powerful model organism for studying the cellular and molecular mechanisms underlying axon regeneration. Various studies from different model organisms have found microtubule dynamics to be pivotal to axon regrowth. In this review, we will discuss the latest findings on how microtubule dynamics are regulated during axon regeneration in C. elegans. Understanding the mechanisms of axon regeneration will aid in the development of more effective therapeutic strategies for treatments of diseases involving disconnection of axons, such as spinal cord injury and stroke.

Idioma originalEnglish (US)
Páginas (desde-hasta)160-166
Número de páginas7
PublicaciónMolecular and Cellular Neuroscience
Volumen91
DOI
EstadoPublished - sept 2018

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Cell Biology

Huella

Profundice en los temas de investigación de 'Microtubules and axon regeneration in C. elegans'. En conjunto forman una huella única.

Citar esto