MicroRNA mediated regulation of immunity against gram-negative bacteria

Jonathon Keck, Rishein Gupta, Lane K. Christenson, Bernard P. Arulanandam

Resultado de la investigación: Review articlerevisión exhaustiva

10 Citas (Scopus)


Evidence over the last couple decades has comprehensively established that short, highly conserved, non-coding RNA species called microRNA (miRNA) exhibit the ability to regulate expression and function of host genes at the messenger RNA (mRNA) level. MicroRNAs play key regulatory roles in immune cell development, differentiation, and protective function. Intrinsic host immune response to invading pathogens rely on intricate orchestrated events in the development of innate and adaptive arms of immunity. We discuss the involvement of miRNAs in regulating these processes against gram negative pathogens in this review.

Idioma originalEnglish (US)
Páginas (desde-hasta)287-299
Número de páginas13
PublicaciónInternational Reviews of Immunology
EstadoPublished - sept 3 2017

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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