Metabolic syndrome: Definition, pathophysiology, and mechanisms

Phillippa J. Miranda, Ralph A. DeFronzo, Robert M. Califf, John R. Guyton

Resultado de la investigación: Articlerevisión exhaustiva

330 Citas (Scopus)

Resumen

Metabolic syndrome is a highly prevalent but under-recognized and undertreated condition. The concurrence of abdominal obesity, borderline hyperglycemia, atherogenic lipoprotein phenotype, and/or hypertension in a patient constitutes a system of linked pathogenesis and high atherogenicity. The complex pathogenetic links involve glucose and fat metabolism, insulin, and a variety of adipocyte-derived hormones and cytokines.

Idioma originalEnglish (US)
Páginas (desde-hasta)33-45
Número de páginas13
PublicaciónAmerican Heart Journal
Volumen149
N.º1
DOI
EstadoPublished - ene. 1 2005

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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