@article{4cc9efce81d5469684cb63fcc8950001,
title = "Metabolic Profiling of Blood and Urine for Exploring the Functional Role of the Microbiota in Human Health",
abstract = "The quantification of metabolites in blood and urine allows nurses to explore new hypotheses about the microbiome. This review summarizes findings from recent studies with a focus on how the state of the science can influence future nursing research initiatives. Metabolomics can advance nursing research by identifying physiologic/pathophysiologic processes underlying patients{\textquoteright} symptoms and can be useful for testing the effects of nursing interventions. To date, metabolomics has been used to study cardiovascular, respiratory, endocrine, autoimmune, and infectious conditions, with research focused on understanding the microbial metabolism of substrates resulting in circulating/excreted biomarkers such as trimethylamine N-oxide. This review provides specific recommendations for the collection of specimens and goals for future studies.",
keywords = "blood, cardiovascular, diabetes, metabolomics, microbiome, nursing, trimethylamine n-oxide, urine",
author = "Diallo, {Ana F.} and Lockwood, {Mark B.} and Maki, {Katherine A.} and Franks, {Alexis T.} and Abhrarup Roy and Rosario Jaime-Lara and Joseph, {Paule V.} and Henderson, {Wendy A.} and Chung, {Seon Yoon} and Jacqueline McGrath and Green, {Stefan J.} and Fink, {Anne M.}",
note = "Funding Information: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: PVJ is supported by the National Institute of Nursing Research under award number 1ZIANR000035-01. PVJ is also supported by the Office of Workforce Diversity, National Institutes of Health and the Rockefeller University Heilbrunn Nurse Scholar Award. AR and ATF received Postbaccalaureate Intramural Research Training Awards, Office of Intramural Training & Education, National Institutes of Health, Department of Health and Human Services. KAM received support from Sigma Theta Tau International Alpha Lambda Chamber, the University of Illinois at Chicago and the International Society of Nurses in Genetics. Funding Information: The authors would like to thank Brigit Sullivan, librarian at the National Institutes of Health (NIH) Library, for reference assistance and Dr. Joan Austin and Melissa Cisewski for their comments in this paper. AFD, PVJ and WAH are forever grateful to Dr. Nicolaas H. Fourie for his mentoring and commitment and contribution to the advancement of nursing science in microbiome research. The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: PVJ is supported by the National Institute of Nursing Research under award number 1ZIANR000035-01. PVJ is also supported by the Office of Workforce Diversity, National Institutes of Health and the Rockefeller University Heilbrunn Nurse Scholar Award. AR and ATF received Postbaccalaureate Intramural Research Training Awards, Office of Intramural Training & Education, National Institutes of Health, Department of Health and Human Services. KAM received support from Sigma Theta Tau International Alpha Lambda Chamber, the University of Illinois at Chicago and the International Society of Nurses in Genetics. Publisher Copyright: {\textcopyright} The Author(s) 2020.",
year = "2020",
month = oct,
day = "1",
doi = "10.1177/1099800420941080",
language = "English (US)",
volume = "22",
pages = "449--457",
journal = "Biological Research for Nursing",
issn = "1099-8004",
publisher = "SAGE Publications Inc.",
number = "4",
}