@inbook{6ee220983d4e4775905c21d80491c4c2,
title = "Mending the Break: Two DNA Double-Strand Break Repair Machines in Eukaryotes",
abstract = "DNA double-strand breaks (DSBs) pose a special challenge for cells in the maintenance of genome stability. In eukaryotes, the removal of DSBs is mediated by two major pathways: homologous recombination (HR) and nonhomologous endjoining (NHEJ). Capitalizing on existing genetic frameworks, biochemical reconstitution studies have begun to yield insights into the mechanistic underpinnings of these DNA repair reactions.",
author = "Lumir Krejci and Ling Chen and Komen, {Stephen Van} and Patrick Sung and Alan Tomkinson",
note = "Funding Information: The studies in the laboratories of the authors have been supported by research grants from the U.S. National Institutes of Health. L.K. was supported in part by a NATO Science Fellowship and S.V.K. was supported in part by a U.S. Army fellowship. We are grateful to Michael Sehorn and Jana Villemain for reading the manuscript.",
year = "2003",
doi = "10.1016/S0079-6603(03)01013-4",
language = "English (US)",
isbn = "0125400748",
series = "Progress in Nucleic Acid Research and Molecular Biology",
publisher = "Academic Press Inc.",
pages = "159--201",
booktitle = "Progress in Nucleic Acid Research and Molecular Biology",
address = "United States",
}