Mass Spectrometry-Based Shotgun Lipidomics for Cancer Research

Jianing Wang, Chunyan Wang, Xianlin Han

Producción científica: Chapter

5 Citas (Scopus)

Resumen

Shotgun lipidomics is an analytical approach for large-scale and systematic analysis of the composition, structure, and quantity of cellular lipids directly from lipid extracts of biological samples by mass spectrometry. This approach possesses advantages of high throughput and quantitative accuracy, especially in absolute quantification. As cancer research deepens at the level of quantitative biology and metabolomics, the demand for lipidomics approaches such as shotgun lipidomics is becoming greater. In this chapter, the principles, approaches, and some applications of shotgun lipidomics for cancer research are overviewed.

Idioma originalEnglish (US)
Título de la publicación alojadaAdvances in Experimental Medicine and Biology
EditorialSpringer
Páginas39-55
Número de páginas17
DOI
EstadoPublished - 2021

Serie de la publicación

NombreAdvances in Experimental Medicine and Biology
Volumen1280
ISSN (versión impresa)0065-2598
ISSN (versión digital)2214-8019

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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