TY - JOUR
T1 - Marijuana in Orthopaedics
T2 - Effects on Bone Health, Wound-Healing, Surgical Complications, and Pain Management
AU - Heath, David M.
AU - Koslosky, Ezekial J.
AU - Bartush, Katherine C.
AU - Hogue, Grant D.
N1 - Publisher Copyright:
© 2022 Journal of Bone and Joint Surgery Inc.. All rights reserved.
PY - 2022/2/21
Y1 - 2022/2/21
N2 - »Marijuana use is on the rise in the United States, and there is a paucity of information on the effects of cannabis and its chemical constituents on bone health, wound-healing, surgical complications, and pain management.»Current evidence suggests that cannabidiol (CBD) may enhance bone health and metabolism, while Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive component in marijuana, has an inhibitory effect.»Marijuana users are at higher risk for delayed bone-healing, demonstrate lower bone mineral density, are at increased risk for fracture, and may experience postoperative complications such as increased opioid use and hyperemesis.
AB - »Marijuana use is on the rise in the United States, and there is a paucity of information on the effects of cannabis and its chemical constituents on bone health, wound-healing, surgical complications, and pain management.»Current evidence suggests that cannabidiol (CBD) may enhance bone health and metabolism, while Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive component in marijuana, has an inhibitory effect.»Marijuana users are at higher risk for delayed bone-healing, demonstrate lower bone mineral density, are at increased risk for fracture, and may experience postoperative complications such as increased opioid use and hyperemesis.
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U2 - 10.2106/JBJS.RVW.21.00184
DO - 10.2106/JBJS.RVW.21.00184
M3 - Review article
C2 - 35180183
AN - SCOPUS:85124930058
SN - 2329-9185
VL - 10
JO - JBJS Reviews
JF - JBJS Reviews
IS - 2
M1 - e21.00184
ER -