Mapping of the DNA locus D4S10 and the linked Huntington’s disease gene to 4p16→p15

B. U. Zabel, Susan L. Naylor, A. Y. Sakaguchi, J. F. Gusella

Resultado de la investigación: Articlerevisión exhaustiva

11 Citas (Scopus)

Resumen

An anonymous DNA fragment (G8) detects two restriction fragment length polymorphic alleles (RFLPs) called D4S10 in Hindill-digested human genomic DNA. This segment had been assigned to chromosome 4 and shows close linkage to the Huntington’s disease gene. With in situ hybridization, we mapped D4SI0 to the terminal region of the short arm of chromosome 4. localizing the Huntington’s disease gene to bands 4p 16→p 15. This information may prove useful for the development of strategics to clone the Huntington’s disease gene.

Idioma originalEnglish (US)
Páginas (desde-hasta)187-190
Número de páginas4
PublicaciónCytogenetic and Genome Research
Volumen42
N.º4
DOI
EstadoPublished - 1986

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Genetics(clinical)

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