LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE

I. L. Cameron; Mary R.H. Pool; T. R. Hoage

doi:10.1111/j.1365-2184.1979.tb00167.x

LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE

I. L. Cameron, Mary R.H. Pool, T. R. Hoage

Resultado de la investigación: Article › revisión exhaustiva

10 Citas (Scopus)

Resumen

Adult mice were pulse labeled with tritiated thymidine [³H]TdR and killed 9 hr later. A low level incorporation of [³H]TdR into the nuclear DNA of Purkinje neurons was found in autoradiographs. Enzymatic digestions with DNase and with RNase in combination with autoradiographic grain counts indicate that a portion of nuclear DNA is not stable in the Purkinje nucleus. These results are discussed in light of reports of the stable nature of DNA in Purkinje neurons of adult mice.

Idioma original	English (US)
Páginas (desde-hasta)	445-451
Número de páginas	7
Publicación	Cell Proliferation
Volumen	12
N.º	4
DOI	https://doi.org/10.1111/j.1365-2184.1979.tb00167.x
Estado	Published - jul. 1979
Publicado de forma externa	Sí

ASJC Scopus subject areas

Cell Biology

Acceder al documento

10.1111/j.1365-2184.1979.tb00167.x

Otros archivos y enlaces

Citar esto

@article{6c1a7526ec474c2798b9085d682aff27,

title = "LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE",

abstract = "Adult mice were pulse labeled with tritiated thymidine [3H]TdR and killed 9 hr later. A low level incorporation of [3H]TdR into the nuclear DNA of Purkinje neurons was found in autoradiographs. Enzymatic digestions with DNase and with RNase in combination with autoradiographic grain counts indicate that a portion of nuclear DNA is not stable in the Purkinje nucleus. These results are discussed in light of reports of the stable nature of DNA in Purkinje neurons of adult mice.",

author = "Cameron, {I. L.} and Pool, {Mary R.H.} and Hoage, {T. R.}",

year = "1979",

month = jul,

doi = "10.1111/j.1365-2184.1979.tb00167.x",

language = "English (US)",

volume = "12",

pages = "445--451",

journal = "Cell Proliferation",

issn = "0008-8730",

publisher = "Wiley-Blackwell",

number = "4",

}

TY - JOUR

T1 - LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE

AU - Cameron, I. L.

AU - Pool, Mary R.H.

AU - Hoage, T. R.

PY - 1979/7

Y1 - 1979/7

N2 - Adult mice were pulse labeled with tritiated thymidine [3H]TdR and killed 9 hr later. A low level incorporation of [3H]TdR into the nuclear DNA of Purkinje neurons was found in autoradiographs. Enzymatic digestions with DNase and with RNase in combination with autoradiographic grain counts indicate that a portion of nuclear DNA is not stable in the Purkinje nucleus. These results are discussed in light of reports of the stable nature of DNA in Purkinje neurons of adult mice.

AB - Adult mice were pulse labeled with tritiated thymidine [3H]TdR and killed 9 hr later. A low level incorporation of [3H]TdR into the nuclear DNA of Purkinje neurons was found in autoradiographs. Enzymatic digestions with DNase and with RNase in combination with autoradiographic grain counts indicate that a portion of nuclear DNA is not stable in the Purkinje nucleus. These results are discussed in light of reports of the stable nature of DNA in Purkinje neurons of adult mice.

UR - http://www.scopus.com/inward/record.url?scp=84982585899&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84982585899&partnerID=8YFLogxK

U2 - 10.1111/j.1365-2184.1979.tb00167.x

DO - 10.1111/j.1365-2184.1979.tb00167.x

M3 - Article

C2 - 476785

AN - SCOPUS:84982585899

VL - 12

SP - 445

EP - 451

JO - Cell Proliferation

JF - Cell Proliferation

SN - 0008-8730

IS - 4

ER -

LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE

Resumen

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto