LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE

I. L. Cameron, Mary R.H. Pool, T. R. Hoage

Resultado de la investigación: Articlerevisión exhaustiva

10 Citas (Scopus)

Resumen

Adult mice were pulse labeled with tritiated thymidine [3H]TdR and killed 9 hr later. A low level incorporation of [3H]TdR into the nuclear DNA of Purkinje neurons was found in autoradiographs. Enzymatic digestions with DNase and with RNase in combination with autoradiographic grain counts indicate that a portion of nuclear DNA is not stable in the Purkinje nucleus. These results are discussed in light of reports of the stable nature of DNA in Purkinje neurons of adult mice.

Idioma originalEnglish (US)
Páginas (desde-hasta)445-451
Número de páginas7
PublicaciónCell Proliferation
Volumen12
N.º4
DOI
EstadoPublished - jul. 1979
Publicado de forma externa

ASJC Scopus subject areas

  • Cell Biology

Huella

Profundice en los temas de investigación de 'LOW LEVEL INCORPORATION OF TRITIATED THYMIDINE INTO THE NUCLEAR DNA OF PURKINJE NEURONS OF ADULT MICE'. En conjunto forman una huella única.

Citar esto