Linezolid-induced black hairy tongue: A case report

Faisal Abdullah Khasawneh, Dereje Fikremariam Moti, Joseph Anthony Zorek

Resultado de la investigación: Articlerevisión exhaustiva

21 Citas (Scopus)

Resumen

Introduction. Linezolid-induced black hairy tongue has been rarely reported. The purpose of this paper is to report a case of linezolid-induced black hairy tongue and review the literature. Case presentation. A 56-year-old Caucasian man was admitted with community-acquired pneumonia that failed to respond to levofloxacin 750mg daily. He was started on linezolid and meropenem and was subsequently discharged home on oral linezolid 600mg every 12 hours and intravenous ertapenem 1g daily. On a follow-up clinic visit, day 14 of linezolid therapy, he complained of dysgeusia and his tongue examination was consistent with black hairy tongue. After he finished his antibiotic course, his complaints resolved with regular tongue brushing. Conclusion: Black hairy tongue is characterized by abnormal hypertrophy and elongation of filiform papillae. Five reported cases of linezolid-induced black hairy tongue were identified in a MEDLINE search (from January 2000 to June 2012). The Naranjo Probability Scale revealed a probable adverse drug reaction of linezolid-induced black hairy tongue. Potential contributing factors included other antibiotics, drug-drug interaction and poor oral hygiene. Health care professionals should be aware of the possibility of linezolid-induced black hairy tongue. Thorough history for other possible contributing factors should be obtained. Patients on linezolid should be counseled to perform good oral hygiene.

Idioma originalEnglish (US)
Número de artículo46
PublicaciónJournal of Medical Case Reports
Volumen7
DOI
EstadoPublished - 2013
Publicado de forma externa

ASJC Scopus subject areas

  • Medicine(all)

Huella

Profundice en los temas de investigación de 'Linezolid-induced black hairy tongue: A case report'. En conjunto forman una huella única.

Citar esto