Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism

Cassidy C. Daw; Karthik Ramachandran; Benjamin T. Enslow; Soumya Maity; Brian Bursic; Matthew J. Novello; Cherubina S. Rubannelsonkumar; Ayah H. Mashal; Joel Ravichandran; Terry M. Bakewell; Weiwei Wang; Kang Li; Travis R. Madaris; Christopher E. Shannon; Luke Norton; Soundarya Kandala; Jeffrey Caplan; Subramanya Srikantan; Peter B. Stathopulos; W. Brian Reeves; Muniswamy Madesh

doi:10.1016/j.cell.2020.08.049

Lactate Elicits ER-Mitochondrial Mg²⁺ Dynamics to Integrate Cellular Metabolism

Cassidy C. Daw
, Karthik Ramachandran
, Benjamin T. Enslow
, Soumya Maity
, Brian Bursic
, Matthew J. Novello
, Cherubina S. Rubannelsonkumar
, Ayah H. Mashal
, Joel Ravichandran
, Terry M. Bakewell
, Weiwei Wang
, Kang Li
, Travis R. Madaris
, Christopher E. Shannon
, Luke Norton
, Soundarya Kandala
, Jeffrey Caplan
, Subramanya Srikantan
, Peter B. Stathopulos
, W. Brian Reeves

Muniswamy Madesh

Producción científica: Article › revisión exhaustiva

213 Citas (Scopus)

Resumen

Lactate operates as a signaling molecule to control Mg²⁺ handling between the ER and mitochondria.

Idioma original	English (US)
Páginas (desde-hasta)	474-489.e17
Publicación	Cell
Volumen	183
N.º	2
DOI	https://doi.org/10.1016/j.cell.2020.08.049
Estado	Published - oct 15 2020

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

Acceder al documento

10.1016/j.cell.2020.08.049

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Daw, C. C., Ramachandran, K., Enslow, B. T., Maity, S., Bursic, B., Novello, M. J., Rubannelsonkumar, C. S., Mashal, A. H., Ravichandran, J., Bakewell, T. M., Wang, W., Li, K., Madaris, T. R., Shannon, C. E., Norton, L., Kandala, S., Caplan, J., Srikantan, S., Stathopulos, P. B., ... Madesh, M. (2020). Lactate Elicits ER-Mitochondrial Mg²⁺ Dynamics to Integrate Cellular Metabolism. Cell, 183(2), 474-489.e17. https://doi.org/10.1016/j.cell.2020.08.049

Daw, CC, Ramachandran, K, Enslow, BT, Maity, S, Bursic, B, Novello, MJ, Rubannelsonkumar, CS, Mashal, AH, Ravichandran, J, Bakewell, TM, Wang, W, Li, K, Madaris, TR, Shannon, CE, Norton, L, Kandala, S, Caplan, J, Srikantan, S, Stathopulos, PB, Reeves, WB & Madesh, M 2020, 'Lactate Elicits ER-Mitochondrial Mg²⁺ Dynamics to Integrate Cellular Metabolism', Cell, vol. 183, n.º 2, pp. 474-489.e17. https://doi.org/10.1016/j.cell.2020.08.049

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title = "Lactate Elicits ER-Mitochondrial Mg2+ Dynamics to Integrate Cellular Metabolism",

abstract = "Lactate operates as a signaling molecule to control Mg2+ handling between the ER and mitochondria.",

keywords = "Mrs2, calcium, cancer, channel, endoplasmic reticulum, inflammation, lactate, magnesium, metabolism, mitochondria",

author = "Daw, \{Cassidy C.\} and Karthik Ramachandran and Enslow, \{Benjamin T.\} and Soumya Maity and Brian Bursic and Novello, \{Matthew J.\} and Rubannelsonkumar, \{Cherubina S.\} and Mashal, \{Ayah H.\} and Joel Ravichandran and Bakewell, \{Terry M.\} and Weiwei Wang and Kang Li and Madaris, \{Travis R.\} and Shannon, \{Christopher E.\} and Luke Norton and Soundarya Kandala and Jeffrey Caplan and Subramanya Srikantan and Stathopulos, \{Peter B.\} and Reeves, \{W. Brian\} and Muniswamy Madesh",

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doi = "10.1016/j.cell.2020.08.049",

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AU - Daw, Cassidy C.

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AU - Enslow, Benjamin T.

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AU - Bursic, Brian

AU - Novello, Matthew J.

AU - Rubannelsonkumar, Cherubina S.

AU - Mashal, Ayah H.

AU - Ravichandran, Joel

AU - Bakewell, Terry M.

AU - Wang, Weiwei

AU - Li, Kang

AU - Madaris, Travis R.

AU - Shannon, Christopher E.

AU - Norton, Luke

AU - Kandala, Soundarya

AU - Caplan, Jeffrey

AU - Srikantan, Subramanya

AU - Stathopulos, Peter B.

AU - Reeves, W. Brian

AU - Madesh, Muniswamy

PY - 2020/10/15

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AB - Lactate operates as a signaling molecule to control Mg2+ handling between the ER and mitochondria.

KW - Mrs2

KW - calcium

KW - cancer

KW - channel

KW - endoplasmic reticulum

KW - inflammation

KW - lactate

KW - magnesium

KW - metabolism

KW - mitochondria

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