TY - GEN
T1 - Investigating brain dynamics and connectivity with functional MRI
AU - Duff, Eugene
AU - Egan, Gary
AU - Cunnington, Ross
AU - Mareels, Iven
AU - Wang, Binquan
AU - Fox, Peter
AU - Xiong, Jinhu
PY - 2004
Y1 - 2004
N2 - Functional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in spontaneous, low frequency brain activity. The physiology underlying these 'resting state' fluctuations is poorly understood. Our current research investigates these networks within the human motor system, assessing their persistence over time, their covariance structure, and the effects that motor performance and training have on the networks. Here we present a review of this study, focusing on the methods involved in assessing the fMRI data, discussing issues of region identification, signal extraction, signal to noise, network covariance analysis and the detection of changes in the networks.
AB - Functional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in spontaneous, low frequency brain activity. The physiology underlying these 'resting state' fluctuations is poorly understood. Our current research investigates these networks within the human motor system, assessing their persistence over time, their covariance structure, and the effects that motor performance and training have on the networks. Here we present a review of this study, focusing on the methods involved in assessing the fMRI data, discussing issues of region identification, signal extraction, signal to noise, network covariance analysis and the detection of changes in the networks.
UR - https://www.scopus.com/pages/publications/28844468931
UR - https://www.scopus.com/pages/publications/28844468931#tab=citedBy
M3 - Conference contribution
AN - SCOPUS:28844468931
SN - 0780388933
SN - 9780780388932
T3 - Proceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04
SP - 565
EP - 570
BT - Proceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04
A2 - Palaniswami, M.
A2 - Krishnamachari, B.
A2 - Sowmya, A.
A2 - Challa, S.
A2 - Palaniswami, M.
A2 - Krishnamachari, B.
A2 - Sowmya, A.
A2 - Challa, S.
T2 - 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04
Y2 - 14 December 2004 through 17 December 2004
ER -