Invasive Aspergillosis: Current Strategies for Diagnosis and Management

Jose Cadena, George R. Thompson, Thomas F. Patterson

Producción científica: Review articlerevisión exhaustiva

108 Citas (Scopus)

Resumen

Aspergillosis remains a significant cause of morbidity and mortality in the immunocompromised population. The spectrum of disease is broad, ranging from severe and rapidly fatal infection to noninvasive disease. The diversity of patients and risk factors complicates diagnostic and therapeutic decision-making. Invasive procedures are often precluded by host status; noninvasive diagnostic tests vary in their sensitivity and specificity. Advancements in understanding the pathophysiology of invasive aspergillosis and host genetics in differential risk have also occurred. Future work may assist in therapeutic decision-making and patient prognosis. Voriconazole remains the preferred agent for treatment. Additional alternatives have emerged.

Idioma originalEnglish (US)
Páginas (desde-hasta)125-142
Número de páginas18
PublicaciónInfectious disease clinics of North America
Volumen30
N.º1
DOI
EstadoPublished - mar 1 2016

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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