Resumen
Human immunodeficiency virus (HIV-1) infected and replicated in primary cultures of normal human ileal and colonic epithelial cells. Monocyte-tropic strains (ADA, 24, and 36) were better able to replicate in the gastrointestinal (GI) cells than the T-cell-tropic HIV strain HTLV-IIIB. In some cultures, virus replication persisted through several months. Intestinal epithelium may be an initial target and reservoir for HIV and a vector for virus dissemination and transmission.
| Idioma original | English (US) |
|---|---|
| Páginas (desde-hasta) | 1409-1415 |
| Número de páginas | 7 |
| Publicación | AIDS Research and Human Retroviruses |
| Volumen | 6 |
| N.º | 12 |
| DOI | |
| Estado | Published - dic 1990 |
ASJC Scopus subject areas
- Immunology
- Virology
- Infectious Diseases
Huella
Profundice en los temas de investigación de 'Infection of Human Gastrointestinal Cells by HIV-1'. En conjunto forman una huella única.Citar esto
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