@inproceedings{51d16b527e5349f3bba3c5e2f9682816,
title = "Improving biomaterials from a cellular point of view",
abstract = "Bioactive glass (6P55), used for coating Ti/Ti-alloy, was tested for its in vitro behavior in a comparative study with commercial Bioglass{\texttrademark} (45S5) and commercial titanium alloy (Ti6Al4V). In vitro testing included pH and dissolution rate determination in simulated body fluid (SBF) along with in vitro cyto-compatibility testing. Similar dissolution behavior was seen for 6P55 and 45S5, demonstrating t1/2 dependence and maximum pH of approximately 8.1 after 10 days of immersion. The dissolution rate of these glasses approached 0 after 15 days of immersion, which resulted in pH stabilization at less than 7.5. Cell culture studies showed that both glasses behaved in a similar fashion after 16 hours in culture. Both glasses had an increase in cell numbers of approximately 200-250%, whereas Ti6Al4V had a less pronounced cell number increase (∼ 180%) relative to initial cell seeding density.",
author = "Varanasi, {V. G.} and T. Vallortigara and Loomer, {P. M.} and E. Saiz and Tomsia, {A. P.} and Marshall, {S. J.} and Marshall, {G. W.}",
year = "2006",
doi = "10.1557/proc-0925-bb03-02",
language = "English (US)",
isbn = "1558998829",
series = "Materials Research Society Symposium Proceedings",
publisher = "Materials Research Society",
pages = "13--19",
booktitle = "Mechanotransduction and Engineered Cell-Surface Interactions",
address = "United States",
note = "2006 MRS Spring Meeting ; Conference date: 17-04-2006 Through 21-04-2006",
}