Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

Anubha Mahajan, Xueling Sim, Hui Jin Ng, Alisa Manning, Manuel A. Rivas, Heather M. Highland, Adam E. Locke, Niels Grarup, Hae Kyung Im, Pablo Cingolani, Jason Flannick, Pierre Fontanillas, Christian Fuchsberger, Kyle J. Gaulton, Tanya M. Teslovich, N. William Rayner, Neil R. Robertson, Nicola L. Beer, Jana K. Rundle, Jette Bork-JensenClaes Ladenvall, Christine Blancher, David Buck, Gemma Buck, Noël P. Burtt, Stacey Gabriel, Anette P. Gjesing, Christopher J. Groves, Mette Hollensted, Jeroen R. Huyghe, Anne U. Jackson, Goo Jun, Johanne Marie Justesen, Massimo Mangino, Jacquelyn Murphy, Matt Neville, Robert Onofrio, Kerrin S. Small, Heather M. Stringham, Ann Christine Syvänen, Joseph Trakalo, Goncalo Abecasis, Graeme I. Bell, John C Blangero, Nancy J. Cox, Ravindranath Duggirala, Craig L. Hanis, Mark Seielstad, James G. Wilson, Cramer Christensen, Ivan Brandslund, Rainer Rauramaa, Gabriela L. Surdulescu, Alex S.F. Doney, Lars Lannfelt, Allan Linneberg, Bo Isomaa, Tiinamaija Tuomi, Marit E. Jørgensen, Torben Jørgensen, Johanna Kuusisto, Matti Uusitupa, Veikko Salomaa, Timothy D. Spector, Andrew D. Morris, Colin N.A. Palmer, Francis S. Collins, Karen L. Mohlke, Richard N. Bergman, Erik Ingelsson, Lars Lind, Jaakko Tuomilehto, Torben Hansen, Richard M. Watanabe, Inga Prokopenko, Josee Dupuis, Fredrik Karpe, Leif Groop, Markku Laakso, Oluf Pedersen, Jose C. Florez, Andrew P. Morris, David Altshuler, James B. Meigs, Michael Boehnke, Mark I. McCarthy, Cecilia M. Lindgren, Anna L. Gloyn, Hanna E Abboud, Uzma Afzal, David Aguilar, Rector Arya, Gil Atzmon, Tin Aung, Eric Banks, Inês Barroso, Nir Barzilai, Jennifer E. Below, Dwaipayan Bharadwaj, Thomas W. Blackwell, Lori L. Bonnycastle, Don Bowden, Jason Carey, Mauricio O. Carneiro, John C. Chambers, Edmund Chan, Juliana Chan, Giriraj R. Chandak, Peng Chen, Yuhui Chen, Han Chen, Ching Yu Cheng, Kee Seng Chia, Yoon Shin Cho, Adolfo Correa, Joanne E Curran, Mark J. Daly, Aaron G. Day-Williams, Ralph A. DeFronzo, Mark DePristo, Peter J. Donnelly, Shah B. Ebrahim, Paul Elliott, Tõnu Esko, João Fadista, Yossi Farjoun, Andrew J. Farmer, Vidya S. Farook, Timothy Fennell, Teresa Ferreira, Tasha Fingerlin, Tom Forsén, Sharon P Fowler, Paul W. Franks, Timothy M. Frayling, Barry I. Freedman, Philippe Froguel, Eric R. Gamazon, Christian Gieger, Benjamin Glaser, Min Jin Go, Jacqueline I. Goldstein, Harald Grallert, George Grant, Todd Green, Michael Griswold, Daniel Esten Hale, Bok Ghee Han, Christopher Hartl, Andrew T. Hattersley, Pamela J. Hicks, Dylan Hodgkiss, Momoko Horikoshi, Martin Hrabé de Angelis, Cheng Hu, Frank B. Hu, Iksoo Huh, Mohammad Kamran Ikram, Thomas Illig, Kathleen A. Jablonski, Christopher P Jenkinson, Weiping Jia, Hyun Min Kang, Chiea Chuen Khor, Yongkang Kim, Young Jin Kim, Bong Jo Kim, Leena Kinnunen, Jaspal Singh Kooner, Jasmina Kravic, Jennifer Kriebel, Ashish Kumar, Satish Kumar, Teemu Kuulasmaa, Min Seok Kwon, Claudia Langenberg, Torsten Lauritzen, Selyeong Lee, Jaehoon Lee, Juyoung Lee, Jong Young Lee, Donna M. Lehman, Benjamin Lehne, Jonathan C. Levy, Jiang Li, Liming Liang, Wei Yen Lim, Keng Han Lin, Jianjun Liu, Marie Loh, Ronald C.W. Ma, Clement Ma, Reedik Mägi, Jared Maguire, Taylor J. Maxwell, Gilean McVean, Christa Meisinger, Thomas Meitinger, Olle Melander, Andres Metspalu, Evelin Mihailov, Lili Milani, Loukas Moutsianas, Martina Müller-Nurasyid, Solomon K. Musani, Yoshihiko Nagai, Narisu Narisu, Benjamin M. Neale, Maggie C.Y. Ng, Peter Nilsson, Stephen P. O'Rahilly, Marju Orho-Melander, Katharine R. Owen, Nicholette D. Palmer, Taesung Park, Dorota Pasko, Richard D. Pearson, John R.B. Perry, Annette Peters, Toni I. Pollin, Ryan Poplin, Dorairaj Prabhakaran, Sobha Puppala, Shaun Purcell, Lu Qi, Qibin Qi, Michael Roden, Olov Rolandsson, Anders H. Rosengren, Manjinder Sandhu, Thomas Schwarzmayr, Laura J. Scott, Robert A. Scott, James Scott, William R. Scott, Jobanpreet Sehmi, Khalid Shakir, Rob Sladek, Joshua D. Smith, Alena Stancáková, Konstantin Strauch, Tim M. Strom, Amy Swift, E. Shyong Tai, Juan Fernandez Tajes, Sian Tsung Tan, Nikhil Tandon, Herman A. Taylor, Yik Ying Teo, Farook Thameem, Barbara Thorand, Martijn van de Bunt, Tibor V. Varga, Mark Walker, Nicholas J. Wareham, Ryan P. Welch, Thomas Wieland, Gregory Wilson, Tien Yin Wong, Andrew R. Wood, Joon Yoon, Eleftheria Zeggini, Weihua Zhang

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Biochemistry, Genetics and Molecular Biology