Hypoglycemic counterregulation in normal and diabetic man

R. A. Gelfand, R. A. DeFronzo

Resultado de la investigación: Review articlerevisión exhaustiva

13 Citas (Scopus)


Insulin-induced hypoglycemia has long represented a troublesome complication in the treatment of diabetes mellitus. This problem has recently gained special significance, as efforts to normalize glycemia in type I diabetics have become increasingly aggressive. With these more vigorous attempts to achieve meticulous metabolic control, and their attendant risk of hypoglycemia, interest has been rekindled in the physiologic mechanisms subserving hypoglycemic counterregulation and how these mechanisms are altered in the insulin-treated diabetic. This review summarizes our current understanding of glucose counterregulation in normal man, with particular emphasis on the important differences observed in patients with type I diabetes.

Idioma originalEnglish (US)
Páginas (desde-hasta)84-93
Número de páginas10
PublicaciónAnnals of Clinical Research
EstadoPublished - ene 1 1984
Publicado de forma externa

ASJC Scopus subject areas

  • Medicine(all)


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