Human platelet stimulation by acetyl glyceryl ether phosphorylcholine

L. M. McManus, D. J. Hanahan, R. N. Pinckard

Producción científica: Articlerevisión exhaustiva

139 Citas (Scopus)

Resumen

Acetyl glyceryl ether phosphorylcholine (AGEPC) induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma. ADP scavengers or indomethacin prevented irreversible platelet aggregation responses induced by 0.2 μM AGEPC but had no effect upon platelet secretion; prostacyclin inhibited AGEPC-induced aggregation and secretion. EDTA or EGTA inhibited AGEPC-induced aggregation but had no effect on platelet secretion.

Idioma originalEnglish (US)
Páginas (desde-hasta)903-906
Número de páginas4
PublicaciónJournal of Clinical Investigation
Volumen67
N.º3
DOI
EstadoPublished - 1981

ASJC Scopus subject areas

  • General Medicine

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