High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons

David I. Levi; Joshua C. Wyrosdic; Amirah Iman Hicks; Mary Ann Andrade; Glenn M. Toney; Masha Prager-Khoutorsky; Charles W. Bourque

doi:10.1016/j.celrep.2021.108866

High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons

David I. Levi, Joshua C. Wyrosdic, Amirah Iman Hicks, Mary Ann Andrade, Glenn M. Toney, Masha Prager-Khoutorsky, Charles W. Bourque

Department of Cellular & Integrative Physiology

Resultado de la investigación: Article › revisión exhaustiva

3 Citas (Scopus)

Resumen

Levi et al. show that rats subjected to two distinct models of salt-dependent hypertension feature an increase in the osmoresponsiveness of neurosecretory neurons that release the antidiuretic and vasoconstrictor hormone vasopressin. However, this common effect is associated with different cellular and synaptic changes that characterize each of the models.

Idioma original	English (US)
Número de artículo	108866
Publicación	Cell Reports
Volumen	34
N.º	11
DOI	https://doi.org/10.1016/j.celrep.2021.108866
Estado	Published - mar 16 2021

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1016/j.celrep.2021.108866

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title = "High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons",

abstract = "Levi et al. show that rats subjected to two distinct models of salt-dependent hypertension feature an increase in the osmoresponsiveness of neurosecretory neurons that release the antidiuretic and vasoconstrictor hormone vasopressin. However, this common effect is associated with different cellular and synaptic changes that characterize each of the models.",

keywords = "angiotensin II, hypertension, mechanosensitivity, osmosensitivity, supraoptic nucleus, vasopressin",

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AU - Wyrosdic, Joshua C.

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AU - Andrade, Mary Ann

AU - Toney, Glenn M.

AU - Prager-Khoutorsky, Masha

AU - Bourque, Charles W.

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KW - angiotensin II

KW - hypertension

KW - mechanosensitivity

KW - osmosensitivity

KW - supraoptic nucleus

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High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons

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