Hem-1, a potential membrane protein, with expression restricted to blood cells

Robert Hromas; Steven Collins; Wendy Raskind; Larry Deaven; Ken Kaushansky

doi:10.1016/0167-4781(91)90109-Y

Hem-1, a potential membrane protein, with expression restricted to blood cells

Robert Hromas
, Steven Collins
, Wendy Raskind
, Larry Deaven
, Ken Kaushansky

Producción científica: Article › revisión exhaustiva

19 Citas (Scopus)

Resumen

Overlapping cDNAs 3.8 kb in lenght containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.

Idioma original	English (US)
Páginas (desde-hasta)	241-244
Número de páginas	4
Publicación	BBA - Gene Structure and Expression
Volumen	1090
N.º	2
DOI	https://doi.org/10.1016/0167-4781(91)90109-Y
Estado	Published - oct 8 1991
Publicado de forma externa	Sí

ASJC Scopus subject areas

Genetics
Structural Biology
Biophysics
Biochemistry

Acceder al documento

10.1016/0167-4781(91)90109-Y

Otros archivos y enlaces

Citar esto

@article{28e6b2f828fc4b7faa18ff1323ebbc96,

title = "Hem-1, a potential membrane protein, with expression restricted to blood cells",

abstract = "Overlapping cDNAs 3.8 kb in lenght containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.",

keywords = "Chromosomal translocations, Hematopoiesis, Membrane protein, Phosphorylation site",

author = "Robert Hromas and Steven Collins and Wendy Raskind and Larry Deaven and Ken Kaushansky",

year = "1991",

month = oct,

day = "8",

doi = "10.1016/0167-4781(91)90109-Y",

language = "English (US)",

volume = "1090",

pages = "241--244",

journal = "BBA - Gene Structure and Expression",

issn = "0167-4781",

publisher = "Elsevier B.V.",

number = "2",

}

TY - JOUR

T1 - Hem-1, a potential membrane protein, with expression restricted to blood cells

AU - Hromas, Robert

AU - Collins, Steven

AU - Raskind, Wendy

AU - Deaven, Larry

AU - Kaushansky, Ken

PY - 1991/10/8

Y1 - 1991/10/8

N2 - Overlapping cDNAs 3.8 kb in lenght containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.

AB - Overlapping cDNAs 3.8 kb in lenght containing a long open reading frame were obtained that hybridized exclusively to transcripts from hematopoietic cells. Sequence analysis found eight potential membrane domains and two possible cAMP/cGMP phosphorylation sites. This sequence exhibited no homologies with the EMBL/Genbank nucleic acid, SwissProt or GenPept amino acid data bases. The gene is located at 12q13.1, a region of occasional translocations in hematopoietic neoplasia and a rare folic acid fragile site, Fra 12A.

KW - Chromosomal translocations

KW - Hematopoiesis

KW - Membrane protein

KW - Phosphorylation site

UR - https://www.scopus.com/pages/publications/0026042148

UR - https://www.scopus.com/pages/publications/0026042148#tab=citedBy

U2 - 10.1016/0167-4781(91)90109-Y

DO - 10.1016/0167-4781(91)90109-Y

M3 - Article

C2 - 1932118

AN - SCOPUS:0026042148

SN - 0167-4781

VL - 1090

SP - 241

EP - 244

JO - BBA - Gene Structure and Expression

JF - BBA - Gene Structure and Expression

IS - 2

ER -

Hem-1, a potential membrane protein, with expression restricted to blood cells

Resumen

ASJC Scopus subject areas

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto