TY - JOUR
T1 - Glomerular epithelium
T2 - Structural alterations induced by polycations
AU - Seiler, M. W.
AU - Venkatachalam, M. A.
AU - Cotran, R. S.
PY - 1975
Y1 - 1975
N2 - Perfusion of rat kidneys with the polycation protamine sulfate caused glomerular epithelial alterations resembling those observed in human and experimental nephrotic states. The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
AB - Perfusion of rat kidneys with the polycation protamine sulfate caused glomerular epithelial alterations resembling those observed in human and experimental nephrotic states. The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
UR - https://www.scopus.com/pages/publications/0016808475
UR - https://www.scopus.com/pages/publications/0016808475#tab=citedBy
U2 - 10.1126/science.1145209
DO - 10.1126/science.1145209
M3 - Article
C2 - 1145209
AN - SCOPUS:0016808475
SN - 0036-8075
VL - 189
SP - 390
EP - 393
JO - Science
JF - Science
IS - 4200
ER -