@article{d2622ac3caab480eaee4312c75aab5be,
title = "GABA receptor modulation of tyrosine hydroxylase gene expression in the rat adrenal gland",
abstract = "Chromaffin cell γ-aminobutyric acid (GABA) receptors play a role in modulating catecholamine secretion. The present experiments examined the role of GABA receptors in modulation of tyrosine hydroxylase (TH) induction in rat adrenal gland. Administration of bicuculline, a GABA antagonist, had no effect on TH activity or TH mRNA. However, bicuculline potentiated reserpine's effect on TH activity and TH mRNA induction. These data suggest that GABA receptors modulate induction of TH and TH mRNA in the adrenal gland.",
keywords = "Adrenal gland, Bicuculline, GABA, Reserpine, Tyrosine hydroxylase, Tyrosine hydroxylase mRNA",
author = "R. Strong and C. Hale and Moore, {M. A.} and M. Wessels-Reiker and Armbrecht, {H. J.} and Richardson, {Arlan G}",
note = "Funding Information: This work was supported by the Geriatric Research, Education and Clinical Center of the St. Louis VA Medical Center, by a grant from the Merit Review Research Program of the Medical Research Service and by NIH Grant AG01548. We thank Dr. Karen O'Malley for her kind donation of the TH.36 cDNA probe.",
year = "1990",
month = sep,
day = "4",
doi = "10.1016/0304-3940(90)90140-5",
language = "English (US)",
volume = "117",
pages = "175--180",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "1-2",
}