Fluorides and non-fluoride remineralization systems

Bennett T. Amaechi, Cor Van Loveren

Resultado de la investigación: Chapter

67 Citas (Scopus)


Caries develops when the equilibrium between de-and remineralization is unbalanced favoring demineralization. De-and remineralization occur depending on the degree of saturation of the interstitial fluids with respect to the tooth mineral. This equilibrium is positively influenced when fluoride, calcium and phosphate ions are added favoring remineralization. In addition, when fluoride is present, it will be incorporated into the newly formed mineral which is then less soluble. Toothpastes may contain fluoride and calcium ions separately or together in various compounds (remineralization systems) and may therefore reduce demineralization and promote remineralization. Formulating all these compounds in one paste may be challenging due to possible premature calcium-fluoride interactions and the low solubility of CaF2. There is a large amount of clinical evidence supporting the potent caries preventive effect of fluoride toothpastes indisputably. The amount of clinical evidence of the effectiveness of the other remineralization systems is far less convincing. Evidence is lacking for head to head comparisons of the various remineralization systems.

Idioma originalEnglish (US)
Título de la publicación alojadaToothpastes
Número de páginas12
EstadoPublished - ago 6 2013

Serie de la publicación

NombreMonographs in Oral Science
ISSN (versión impresa)0077-0892
ISSN (versión digital)1662-3843

ASJC Scopus subject areas

  • Dentistry(all)


Profundice en los temas de investigación de 'Fluorides and non-fluoride remineralization systems'. En conjunto forman una huella única.

Citar esto