Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C

R. A. Hromas; D. E. Markel; V. E. Scholes

Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C

R. A. Hromas
, D. E. Markel
, V. E. Scholes

Producción científica: Article › revisión exhaustiva

Resumen

Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase.

Idioma original	English (US)
Páginas (desde-hasta)	365-368
Número de páginas	4
Publicación	Research Communications in Chemical Pathology and Pharmacology
Volumen	30
N.º	2
Estado	Published - 1980
Publicado de forma externa	Sí

ASJC Scopus subject areas

General Pharmacology, Toxicology and Pharmaceutics
Pathology and Forensic Medicine
Toxicology
Pharmacology

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title = "Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C",

abstract = "Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase.",

author = "Hromas, \{R. A.\} and Markel, \{D. E.\} and Scholes, \{V. E.\}",

year = "1980",

language = "English (US)",

volume = "30",

pages = "365--368",

journal = "Research Communications in Chemical Pathology and Pharmacology",

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T1 - Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C

AU - Hromas, R. A.

AU - Markel, D. E.

AU - Scholes, V. E.

PY - 1980

Y1 - 1980

N2 - Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase.

AB - Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase.

UR - https://www.scopus.com/pages/publications/0019197698

UR - https://www.scopus.com/pages/publications/0019197698#tab=citedBy

M3 - Article

C2 - 7444164

AN - SCOPUS:0019197698

SN - 0034-5164

VL - 30

SP - 365

EP - 368

JO - Research Communications in Chemical Pathology and Pharmacology

JF - Research Communications in Chemical Pathology and Pharmacology

IS - 2

ER -

Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ara-C

Resumen

ASJC Scopus subject areas

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Huella

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