Flow increases endothelial migration and inhibits smooth muscle cell proliferation in artery and co-culture models

Yong Ung Lee, Jian Luo, Eugene Sprague, Hai Chao Han

Producción científica: Conference contribution

Resumen

Arterial restenosis associated with intimai hyperplasia at stent revascularization sites remains the major cause of long-term failure. The objective of this study was to determine the effect of flow in promoting endothelial cell migration and the effect of reendothelialization on smooth muscle cell (SMC) proliferation. This study demonstrated that re-endothelialization reduces SMC proliferation and migration and provides model systems to study approaches to increasing endothelial healing.

Idioma originalEnglish (US)
Título de la publicación alojadaProceedings of the ASME Summer Bioengineering Conference, SBC2008
Páginas305-306
Número de páginas2
EdiciónPART A
EstadoPublished - 2009
Publicado de forma externa
Evento10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States
Duración: jun 25 2008jun 29 2008

Serie de la publicación

NombreProceedings of the ASME Summer Bioengineering Conference, SBC2008
NúmeroPART A

Other

Other10th ASME Summer Bioengineering Conference, SBC2008
País/TerritorioUnited States
CiudadMarco Island, FL
Período6/25/086/29/08

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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