Extensive transcription of foreign DNA in a crown gall teratoma

Funmei Yang; Joan C. McPherson; Milton P. Gordon; Eugene W. Nester

doi:10.1016/0006-291X(80)90424-6

Extensive transcription of foreign DNA in a crown gall teratoma

Funmei Yang, Joan C. McPherson, Milton P. Gordon, Eugene W. Nester

Resultado de la investigación: Article › revisión exhaustiva

15 Citas (Scopus)

Resumen

We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

Idioma original	English (US)
Páginas (desde-hasta)	1273-1277
Número de páginas	5
Publicación	Biochemical and Biophysical Research Communications
Volumen	92
N.º	4
DOI	https://doi.org/10.1016/0006-291X(80)90424-6
Estado	Published - feb 27 1980
Publicado de forma externa	Sí

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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title = "Extensive transcription of foreign DNA in a crown gall teratoma",

abstract = "We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.",

author = "Funmei Yang and McPherson, {Joan C.} and Gordon, {Milton P.} and Nester, {Eugene W.}",

note = "Funding Information: in the preparation Bst I and BST EII were supported by Public Institute.",

year = "1980",

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doi = "10.1016/0006-291X(80)90424-6",

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AU - Yang, Funmei

AU - McPherson, Joan C.

AU - Gordon, Milton P.

AU - Nester, Eugene W.

N1 - Funding Information: in the preparation Bst I and BST EII were supported by Public Institute.

PY - 1980/2/27

Y1 - 1980/2/27

N2 - We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

AB - We detected polyadenylated RNA transcripts of the portion of A. tumefaciens tumor inducing plasmid DNA incorporated into a crown gall teratoma tumor, BT37. Our results indicate that transcription occurs throughout the plasmid sequences in the tumor tissue. Those DNA sequences which are essential for oncogenicity and nopaline sysnthesis are most heavily transcribed. Possible functions of these polyadenylated transcripts are discussed.

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U2 - 10.1016/0006-291X(80)90424-6

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JO - Biochemical and Biophysical Research Communications

JF - Biochemical and Biophysical Research Communications

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ER -

Extensive transcription of foreign DNA in a crown gall teratoma

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