Experimentally-induced diabetes reduces nocturnal pineal melatonin content in the Syrian hamster

Thomas H. Champney, George C. Brainard, Bruce A. Richardson, Russel J. Reiter

Producción científica: Articlerevisión exhaustiva

41 Citas (Scopus)

Resumen

1. 1. Male, Syrian hamsters were rendered diabetic by either alloxan (60mg/kg, i.v.) or streptozotocin (65 mg/kg, i.p.). 2. 2. Diabetic animals had reduced pineal melatonin contents during the night. Basal daytime values were not significantly altered. 3. 3. Diabetes may decrease melatonin synthesis by reducing the availability of glucose for metabolism or by decreasing the transport of tryptophan into pinealocytes for the synthesis of melatonin.

Idioma originalEnglish (US)
Páginas (desde-hasta)199-201
Número de páginas3
PublicaciónComparative Biochemistry and Physiology -- Part A: Physiology
Volumen76
N.º1
DOI
EstadoPublished - 1983

ASJC Scopus subject areas

  • Physiology

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