Evolutionary conservation between budding yeast and human kinetochores

Katsumi Kitagawa; Philip Hieter

doi:10.1038/35089568

Evolutionary conservation between budding yeast and human kinetochores

Katsumi Kitagawa
, Philip Hieter

Producción científica: Review article › revisión exhaustiva

95 Citas (Scopus)

Resumen

Accurate chromosome segregation during mitosis requires the correct assembly of kinetochores - complexes of centromeric DNA and proteins that link chromosomes to spindle microtubules. Studies on the kinetochore of the budding yeast Saccharomyces cerevisiae have revealed functionally novel components of the kinetochore and its regulatory complexes, some of which are highly conserved in humans.

Idioma original	English (US)
Páginas (desde-hasta)	678-687
Número de páginas	10
Publicación	Nature Reviews Molecular Cell Biology
Volumen	2
N.º	9
DOI	https://doi.org/10.1038/35089568
Estado	Published - sept 2001
Publicado de forma externa	Sí

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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title = "Evolutionary conservation between budding yeast and human kinetochores",

abstract = "Accurate chromosome segregation during mitosis requires the correct assembly of kinetochores - complexes of centromeric DNA and proteins that link chromosomes to spindle microtubules. Studies on the kinetochore of the budding yeast Saccharomyces cerevisiae have revealed functionally novel components of the kinetochore and its regulatory complexes, some of which are highly conserved in humans.",

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AU - Hieter, Philip

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AB - Accurate chromosome segregation during mitosis requires the correct assembly of kinetochores - complexes of centromeric DNA and proteins that link chromosomes to spindle microtubules. Studies on the kinetochore of the budding yeast Saccharomyces cerevisiae have revealed functionally novel components of the kinetochore and its regulatory complexes, some of which are highly conserved in humans.

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UR - https://www.scopus.com/pages/publications/0035462116#tab=citedBy

U2 - 10.1038/35089568

DO - 10.1038/35089568

M3 - Review article

C2 - 11533725

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EP - 687

JO - Nature Reviews Molecular Cell Biology

JF - Nature Reviews Molecular Cell Biology

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Evolutionary conservation between budding yeast and human kinetochores

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