Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

George R. Thompson; Annette W. Fothergill; Nathan P. Wiederhold; Ana C. Vallor; Brian L. Wickes; Thomas F. Patterson

doi:10.1128/AAC.00646-08

Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

George R. Thompson
, Annette W. Fothergill
, Nathan P. Wiederhold
, Ana C. Vallor
, Brian L. Wickes
, Thomas F. Patterson

Producción científica: Article › revisión exhaustiva

31 Citas (Scopus)

Resumen

We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

Idioma original	English (US)
Páginas (desde-hasta)	2959-2961
Número de páginas	3
Publicación	Antimicrobial agents and chemotherapy
Volumen	52
N.º	8
DOI	https://doi.org/10.1128/AAC.00646-08
Estado	Published - ago 2008

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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abstract = "We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8\% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.",

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AU - Wickes, Brian L.

AU - Patterson, Thomas F.

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AB - We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

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Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans

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