Evaluation of antioxidant activity and characterization of phenolic constituents of Phyllanthus amarus root

Soumya Maity, Suchandra Chatterjee, Prasad Shekhar Variyar, Arun Sharma, Soumyakanti Adhikari, Santasree Mazumder

Producción científica: Articlerevisión exhaustiva

41 Citas (Scopus)

Resumen

The antioxidant property of the 70% aqueous ethanol extract of Phyllanthus amarus roots and its ether-soluble, ethyl acetate-soluble, and aqueous fractions were investigated by various in vitro assays. The root extracts showed higher DPPH, hydroxyl, superoxide, and nitric oxide radical scavenging and reducing power activity. Among all the samples, the ethyl acetate-soluble fraction demonstrated highest radical scavenging activity and total phenolics content. Twenty-eight different phenolic compounds were identified by LCMS/MS analysis of the ethyl acetate-soluble fraction. The majority of the compounds were found to exist as their glycosides, and many of these were gallic acid derivatives. Free epicatechin and gallic acid were also identified in the ethyl acetate-soluble fraction. The present investigation suggested that P. amarus root is a potent antioxidant and can be used for the prevention of diseases related to oxidative stress.

Idioma originalEnglish (US)
Páginas (desde-hasta)3443-3450
Número de páginas8
PublicaciónJournal of Agricultural and Food Chemistry
Volumen61
N.º14
DOI
EstadoPublished - abr 10 2013

ASJC Scopus subject areas

  • General Chemistry
  • General Agricultural and Biological Sciences

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