Epidemiology of myeloproliferative neoplasms in the United States

Jyotsna Mehta, Hongwei Wang, Sheikh Usman Iqbal, Ruben Mesa

Resultado de la investigación: Articlerevisión exhaustiva

151 Citas (Scopus)


Myelofibrosis (MF), polycythemia vera (PV) and essential thrombocythemia (ET) are three classic BCR ABL fusion gene-negative chronic myeloproliferative neoplasms (MPNs). Though rare, it is important to understand the burden of illness of these disorders for public health planning, healthcare insurers and pharmaceutical manufacturers. Therefore, we have described the incidence of MF and prevalence of MF, ET and PV in the United States between 2008 and 2010 based on data from two large health plans. The incidence of primary MF was about 1 per 100 000 per year and did not vary over the study years. The prevalence of PV (44-57 per 100 000) and ET (38-57 per 100 000) was much higher than that of MF (4-6 per 100 000) or subgroups containing MF (post-PV MF = 0.3-0.7 per 100 000; post-ET MF = 0.5-1.1 per 100 000). Additional research using other national databases and/or study designs is needed to substantiate these findings.

Idioma originalEnglish (US)
Páginas (desde-hasta)595-600
Número de páginas6
PublicaciónLeukemia and Lymphoma
EstadoPublished - mar 2014
Publicado de forma externa

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research


Profundice en los temas de investigación de 'Epidemiology of myeloproliferative neoplasms in the United States'. En conjunto forman una huella única.

Citar esto