Endothelium-Derived Nitric Oxide as an Antiatherogenic Mechanism: Implications for Therapy

Roman A. Sukhovershin; Gautham Yepuri; Yohannes T. Ghebremariam

doi:10.14797/mdcj-11-3-166

Endothelium-Derived Nitric Oxide as an Antiatherogenic Mechanism: Implications for Therapy

Roman A. Sukhovershin
, Gautham Yepuri
, Yohannes T. Ghebremariam

Producción científica: Review article › revisión exhaustiva

46 Citas (Scopus)

Resumen

Endothelium-derived nitric oxide (eNO) is a multifunctional signaling molecule critically involved in the maintenance of metabolic and cardiovascular homeostasis. In addition to its role as a potent endogenous vasodilator, eNO suppresses key processes in vascular lesion formation and opposes atherogenesis. This review discusses eNO as an antiatherogenic molecule and highlights factors that influence its bioavailability and therapeutic approaches to restore or enhance its levels.

Idioma original	English (US)
Páginas (desde-hasta)	166-171
Número de páginas	6
Publicación	Methodist DeBakey cardiovascular journal
Volumen	11
N.º	3
DOI	https://doi.org/10.14797/mdcj-11-3-166
Estado	Published - jul 1 2015
Publicado de forma externa	Sí

ASJC Scopus subject areas

General Medicine

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abstract = "Endothelium-derived nitric oxide (eNO) is a multifunctional signaling molecule critically involved in the maintenance of metabolic and cardiovascular homeostasis. In addition to its role as a potent endogenous vasodilator, eNO suppresses key processes in vascular lesion formation and opposes atherogenesis. This review discusses eNO as an antiatherogenic molecule and highlights factors that influence its bioavailability and therapeutic approaches to restore or enhance its levels.",

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KW - dimethylarginine dimethylaminohydrolase

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Endothelium-Derived Nitric Oxide as an Antiatherogenic Mechanism: Implications for Therapy

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