Effects of morphine and methadone on the nuclear uptake of estradiol by the brain

Peter J. Sheridan

doi:10.3109/15563657808988246

Effects of morphine and methadone on the nuclear uptake of estradiol by the brain

Peter J. Sheridan

Resultado de la investigación: Article › revisión exhaustiva

Idioma original	English (US)
Páginas (desde-hasta)	383-390
Número de páginas	8
Publicación	Clinical Toxicology
Volumen	13
N.º	3
DOI	https://doi.org/10.3109/15563657808988246
Estado	Published - 1978
Publicado de forma externa	Sí

ASJC Scopus subject areas

Toxicology

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10.3109/15563657808988246

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title = "Effects of morphine and methadone on the nuclear uptake of estradiol by the brain",

author = "Sheridan, {Peter J.}",

note = "Funding Information: The mechanism( s) by which morphine and methadone alter hypothalamic-hypophyseal function is not known at present. Recently, both methadone and morphine have been reported to competitively inhibit the binding of testosterone to liver microsomes, and it was suggested that the opiates mimic the steroids by binding to steroid hormone re- ceptors [ 161. Since preovulatory rise of estradiol is essential for the *This work was supported in part by USPHS Research Career De- velopment Award 1 KO4 NS 000164 and USPHS Grant DA R01 DA-01622.",

year = "1978",

doi = "10.3109/15563657808988246",

language = "English (US)",

volume = "13",

pages = "383--390",

journal = "Clinical Toxicology",

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N1 - Funding Information: The mechanism( s) by which morphine and methadone alter hypothalamic-hypophyseal function is not known at present. Recently, both methadone and morphine have been reported to competitively inhibit the binding of testosterone to liver microsomes, and it was suggested that the opiates mimic the steroids by binding to steroid hormone re- ceptors [ 161. Since preovulatory rise of estradiol is essential for the *This work was supported in part by USPHS Research Career De- velopment Award 1 KO4 NS 000164 and USPHS Grant DA R01 DA-01622.

PY - 1978

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