Effect of tocolytic agents on fetal umbilical velocimetry

Jeffrey W. Wright, Robert M. Patterson, Louis E. Ridgway, Michael D. Berkus

Producción científica: Articlerevisión exhaustiva

9 Citas (Scopus)


In this prospective study, we sought to examine the changes in umbilical vascular resistance induced by tocolytic therapy. Umbilical artery velocimetry was performed in 46 patients with preterm labor before tocolysis and at 1 hour and 24 hours after tocolysis was initiated. Raw systolic/diastolic ratios were corrected for concomitant changes in fetal heart rate. Thirty patients received subcutaneous terbutaline and 16 were treated with intravenous magnesium. Systolic/diastolic ratios decreased in patients treated with terbutaline. This decline persisted after correction for increases in fetal heart rate. No significant changes in systolic/diastolic ratios were seen in patients treated with magnesium. We conclude that terbutaline may affect umbilical vascular resistance. Possible clinical implications of these findings are discussed.

Idioma originalEnglish (US)
Páginas (desde-hasta)748-750
Número de páginas3
PublicaciónAmerican Journal of Obstetrics and Gynecology
EstadoPublished - sept 1990

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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