Mice infected in the genital tract with the Chlamydia trachomatis agent of mouse pneumonitis were treated with monoclonal rat anti-gamma interferon (anti-IFN-γ) antibody to determine whether IFN-γ participated in the resolution of the infection. In two experiments, anti-IFN-γ antibody treatment resulted in significantly prolonged infections. In support of these data, passive administration of recombinant IFN-γ to chronically infected nu/nu mice was able to bring about resolution of the infection in some animals.
|Idioma original||English (US)|
|Número de páginas||3|
|Publicación||Infection and immunity|
|Estado||Published - 1992|
|Publicado de forma externa||Sí|
ASJC Scopus subject areas
- Infectious Diseases