TY - JOUR
T1 - Economic Disadvantage During Childhood, Obesity, and Diabetes Across Three Birth Cohorts of Older Mexicans
AU - Zazueta-Borboa, Jesús Daniel
AU - Samper-Ternent, Rafael
AU - Wong, Rebeca
AU - Mehta, Neil
N1 - Publisher Copyright:
© The Author(s) 2024. Published by Oxford University Press on behalf of The Gerontological Society of America.
PY - 2024/12/1
Y1 - 2024/12/1
N2 - Objectives: Diabetes prevalence has increased markedly in Mexico. We examined the individual and joint contributions of economic disadvantage during childhood (EDDC) and elevated body weight on diabetes prevalence in 3 cohorts of Mexican adults. Methods: Data on those 60–69 years old from the 1930–1939, 1940–1949, and 1950–1959 birth cohorts in Waves 1 (2001), 3 (2012), and 5 (2018) of the Mexican Health and Aging Study were used. EDDC was defined as the absence of a toilet in the household before age 10. Body mass status was defined using self-reported perceived body image at age 50. Diabetes was based on respondent reports. Supplementary analyses using HbA1c as a criterion for diabetes were conducted. A regression-decomposition approach was implemented. Logistic regression models included adjustments for sociodemographic characteristics and access to medical care. Results: Diabetes prevalence was 23% overall and 11%, 25%, and 26% in the 1930–1939, 1940–1949, and 1950–1959 cohorts, respectively. EDDC declined across successive cohorts, whereas the prevalence of overweight/obesity at age 50 increased. EDDC and overweight/obesity were associated with higher odds of reporting diabetes. A scenario that eliminates disadvantaged EDDC reduced diabetes prevalence by 11% in a pooled sample, while eliminating overweight/obesity reduced it by 30%. Overweight/obesity explained 42% of the rise in diabetes prevalence between the 1930–1939 and 1950–1959 cohorts. Improvement in EDDC explained 18% of the rise in diabetes prevalence between 1930–1939 and 1950–1959 cohorts. Discussion: High body weight across Mexican birth cohorts seemed to offset the potential benefits from improvements in childhood conditions on adult diabetes risk.
AB - Objectives: Diabetes prevalence has increased markedly in Mexico. We examined the individual and joint contributions of economic disadvantage during childhood (EDDC) and elevated body weight on diabetes prevalence in 3 cohorts of Mexican adults. Methods: Data on those 60–69 years old from the 1930–1939, 1940–1949, and 1950–1959 birth cohorts in Waves 1 (2001), 3 (2012), and 5 (2018) of the Mexican Health and Aging Study were used. EDDC was defined as the absence of a toilet in the household before age 10. Body mass status was defined using self-reported perceived body image at age 50. Diabetes was based on respondent reports. Supplementary analyses using HbA1c as a criterion for diabetes were conducted. A regression-decomposition approach was implemented. Logistic regression models included adjustments for sociodemographic characteristics and access to medical care. Results: Diabetes prevalence was 23% overall and 11%, 25%, and 26% in the 1930–1939, 1940–1949, and 1950–1959 cohorts, respectively. EDDC declined across successive cohorts, whereas the prevalence of overweight/obesity at age 50 increased. EDDC and overweight/obesity were associated with higher odds of reporting diabetes. A scenario that eliminates disadvantaged EDDC reduced diabetes prevalence by 11% in a pooled sample, while eliminating overweight/obesity reduced it by 30%. Overweight/obesity explained 42% of the rise in diabetes prevalence between the 1930–1939 and 1950–1959 cohorts. Improvement in EDDC explained 18% of the rise in diabetes prevalence between 1930–1939 and 1950–1959 cohorts. Discussion: High body weight across Mexican birth cohorts seemed to offset the potential benefits from improvements in childhood conditions on adult diabetes risk.
KW - Cohorts
KW - Early childhood conditions
KW - MHAS
KW - Mexico
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U2 - 10.1093/geronb/gbae178
DO - 10.1093/geronb/gbae178
M3 - Article
C2 - 39470403
AN - SCOPUS:85210762599
SN - 1079-5014
VL - 79
JO - Journals of Gerontology - Series B Psychological Sciences and Social Sciences
JF - Journals of Gerontology - Series B Psychological Sciences and Social Sciences
IS - 12
M1 - gbae178
ER -