Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections

Nicholas Rebold; Taylor Morrisette; Abdalhamid M. Lagnf; Sara Alosaimy; Dana Holger; Katie Barber; Julie Ann Justo; Kayla Antosz; Travis J. Carlson; Jeremy J. Frens; Mark Biagi; Wesley D. Kufel; William J. Moore; Nicholas Mercuro; Brian R. Raux; Michael J. Rybak

doi:10.1093/ofid/ofab554

Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections

Nicholas Rebold
, Taylor Morrisette
, Abdalhamid M. Lagnf
, Sara Alosaimy
, Dana Holger
, Katie Barber
, Julie Ann Justo
, Kayla Antosz
, Travis J. Carlson
, Jeremy J. Frens
, Mark Biagi
, Wesley D. Kufel
, William J. Moore
, Nicholas Mercuro
, Brian R. Raux
, Michael J. Rybak

Producción científica: Article › revisión exhaustiva

29 Citas (Scopus)

Resumen

A multicenter case series of 21 patients were treated with imipenem-cilastatin-relebactam. There were mixed infection sources, with pulmonary infections (11/21,52%) composing the majority. The primary pathogen was Pseudomonas aeruginosa (16/21, 76%), and 15/16 (94%) isolates were multidrug-resistant. Thirty-day survival occurred in 14/21 (67%) patients. Two patients experienced adverse effects.

Idioma original	English (US)
Número de artículo	ofab554
Publicación	Open Forum Infectious Diseases
Volumen	8
N.º	12
DOI	https://doi.org/10.1093/ofid/ofab554
Estado	Published - dic 1 2021
Publicado de forma externa	Sí

ASJC Scopus subject areas

Oncology
Infectious Diseases

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Rebold, N., Morrisette, T., Lagnf, A. M., Alosaimy, S., Holger, D., Barber, K., Justo, J. A., Antosz, K., Carlson, T. J., Frens, J. J., Biagi, M., Kufel, W. D., Moore, W. J., Mercuro, N., Raux, B. R., & Rybak, M. J. (2021). Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections. Open Forum Infectious Diseases, 8(12), Artículo ofab554. https://doi.org/10.1093/ofid/ofab554

Rebold, N, Morrisette, T, Lagnf, AM, Alosaimy, S, Holger, D, Barber, K, Justo, JA, Antosz, K, Carlson, TJ, Frens, JJ, Biagi, M, Kufel, WD, Moore, WJ, Mercuro, N, Raux, BR & Rybak, MJ 2021, 'Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections', Open Forum Infectious Diseases, vol. 8, n.º 12, ofab554. https://doi.org/10.1093/ofid/ofab554

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title = "Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections",

abstract = "A multicenter case series of 21 patients were treated with imipenem-cilastatin-relebactam. There were mixed infection sources, with pulmonary infections (11/21,52\%) composing the majority. The primary pathogen was Pseudomonas aeruginosa (16/21, 76\%), and 15/16 (94\%) isolates were multidrug-resistant. Thirty-day survival occurred in 14/21 (67\%) patients. Two patients experienced adverse effects.",

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Early Multicenter Experience With Imipenem-Cilastatin-Relebactam for Multidrug-Resistant Gram-Negative Infections

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ASJC Scopus subject areas

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