Dynamic changes in the cerebral metabolic rate of O2 and oxygen extraction ratio in event-related functional MRI

Ching Mei Feng, Ho Ling Liu, Peter T. Fox, Jia Hong Gao

Producción científica: Articlerevisión exhaustiva

8 Citas (Scopus)

Resumen

Dynamic changes in the cerebral metabolic rate of oxygen (CMRO2) and oxygen extraction ratio (OER) in an event-related functional MRI (ER-fMRI) were measured in this study. Six subjects participated in this study at a magnetic field of 1.9 T. Cerebral blood flow (CBF) and blood oxygenation level-dependent (BOLD) changes were acquired during the brief visual stimulation, and the corresponding changes in CMRO2 and OER were then determined. The results showed that the maximum relative changes in CMRO2 and OER were about 10.36 ± 0.85 and -6.54 ± 0.55%, respectively, while the maximum changes in CBF and BOLD were approximately 17.35 ± 1.37 and 1.03 ± 0.06%, respectively. The CBF, CMRO2, and OER changes reach their maximum approximately 1 s earlier than the BOLD signal change (4.15 ± 0.21, 4.16 ± 0.21, and 4.17 ± 0.21 s vs 5.12 ± 0.24 s after stimulation, P < 0.05).

Idioma originalEnglish (US)
Páginas (desde-hasta)257-262
Número de páginas6
PublicaciónNeuroImage
Volumen18
N.º2
DOI
EstadoPublished - feb 1 2003

ASJC Scopus subject areas

  • Neurology
  • Cognitive Neuroscience

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