Does Outflow Obstruction Exist in Hypertrophic Cardiomyopathy?

Producción científica: Editorialrevisión exhaustiva

26 Citas (Scopus)


In this issue of the Journal, Pollick's report1 focuses on the ability of disopyramide to reduce or eliminate the echocardiographic and hemodynamic signs of left ventricular “outflow obstruction” in a small number of patients with muscular subaortic stenosis. This study suggests that the negative inotropic actions of this drug may produce hemodynamic improvement and increase exercise tolerance by eliminating intraventricular gradients. Although this study was uncontrolled and its conclusions must be considered preliminary, it does raise an important question: Is left ventricular outflow truly obstructed in hypertrophic cardiomyopathy? Since the concept of a functional stenosis of the left ventricle.

Idioma originalEnglish (US)
Páginas (desde-hasta)1008-1009
Número de páginas2
PublicaciónNew England Journal of Medicine
EstadoPublished - oct 14 1982

ASJC Scopus subject areas

  • General Medicine


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