Diurnal fluctuation in dna content and DNA synthesis in the dorsal epidermis of Rana pipiens

William W. Morgan; Sherwin Mizell

doi:10.1016/0300-9629(71)90126-5

Diurnal fluctuation in dna content and DNA synthesis in the dorsal epidermis of Rana pipiens

William W. Morgan, Sherwin Mizell

Resultado de la investigación: Article › revisión exhaustiva

12 Citas (Scopus)

Resumen

1. 1. DNA content and DNA synthesis (³H-thymidine uptake) were measured in dorsal skin epidermis of frogs-Rana pipiens sacrificed in groups of 12 over a period of 24 hr-exposed to a 12 : 12 light-dark lighting régime for 2 weeks before sacrifice. 2. 2. Diurnal fluctuations were observed in both DNA content and DNA synthesis of dorsal epidermis. 3. 3. The reproducibility of these rhythms suggests that they are true physiological phenomena with periodicities of nearly 24 hr. 4. 4. The results of light inversion experiments suggest the importance of the lighting régime in the regulation of these rhythms.

Idioma original	English (US)
Páginas (desde-hasta)	591-602
Número de páginas	12
Publicación	Comparative Biochemistry and Physiology -- Part A: Physiology
Volumen	38
N.º	3
DOI	https://doi.org/10.1016/0300-9629(71)90126-5
Estado	Published - mar. 1 1971
Publicado de forma externa	Sí

ASJC Scopus subject areas

Physiology

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10.1016/0300-9629(71)90126-5

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@article{89e7f60df61d443293e5af1eac63b5cd,

title = "Diurnal fluctuation in dna content and DNA synthesis in the dorsal epidermis of Rana pipiens",

abstract = "1. 1. DNA content and DNA synthesis (3H-thymidine uptake) were measured in dorsal skin epidermis of frogs-Rana pipiens sacrificed in groups of 12 over a period of 24 hr-exposed to a 12 : 12 light-dark lighting r{\'e}gime for 2 weeks before sacrifice. 2. 2. Diurnal fluctuations were observed in both DNA content and DNA synthesis of dorsal epidermis. 3. 3. The reproducibility of these rhythms suggests that they are true physiological phenomena with periodicities of nearly 24 hr. 4. 4. The results of light inversion experiments suggest the importance of the lighting r{\'e}gime in the regulation of these rhythms.",

keywords = "H-thymidine uptake, cell division, Circadian rhythm, diurnal fluctuations, DNA content, DNA synthesis, exogenous stimulus, frog metabolism, growth, lighting r{\'e}gime, Rana pipiens, rhythms",

author = "Morgan, {William W.} and Sherwin Mizell",

note = "Funding Information: * Supported by NASA grant No. 15-003-053. Submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy of the Graduate School, Indiana University, Bloomington, Indiana. t Supported by N.S.F. fellowship No. 48-430-02 and P.H.S. fellowship No. GM-39131. Current address: Department of Anatomy, University of Texas Medical School at San Antonio, San Antonio, Texas 78229.",

year = "1971",

month = mar,

day = "1",

doi = "10.1016/0300-9629(71)90126-5",

language = "English (US)",

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T1 - Diurnal fluctuation in dna content and DNA synthesis in the dorsal epidermis of Rana pipiens

AU - Morgan, William W.

AU - Mizell, Sherwin

N1 - Funding Information: * Supported by NASA grant No. 15-003-053. Submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy of the Graduate School, Indiana University, Bloomington, Indiana. t Supported by N.S.F. fellowship No. 48-430-02 and P.H.S. fellowship No. GM-39131. Current address: Department of Anatomy, University of Texas Medical School at San Antonio, San Antonio, Texas 78229.

PY - 1971/3/1

Y1 - 1971/3/1

N2 - 1. 1. DNA content and DNA synthesis (3H-thymidine uptake) were measured in dorsal skin epidermis of frogs-Rana pipiens sacrificed in groups of 12 over a period of 24 hr-exposed to a 12 : 12 light-dark lighting régime for 2 weeks before sacrifice. 2. 2. Diurnal fluctuations were observed in both DNA content and DNA synthesis of dorsal epidermis. 3. 3. The reproducibility of these rhythms suggests that they are true physiological phenomena with periodicities of nearly 24 hr. 4. 4. The results of light inversion experiments suggest the importance of the lighting régime in the regulation of these rhythms.

AB - 1. 1. DNA content and DNA synthesis (3H-thymidine uptake) were measured in dorsal skin epidermis of frogs-Rana pipiens sacrificed in groups of 12 over a period of 24 hr-exposed to a 12 : 12 light-dark lighting régime for 2 weeks before sacrifice. 2. 2. Diurnal fluctuations were observed in both DNA content and DNA synthesis of dorsal epidermis. 3. 3. The reproducibility of these rhythms suggests that they are true physiological phenomena with periodicities of nearly 24 hr. 4. 4. The results of light inversion experiments suggest the importance of the lighting régime in the regulation of these rhythms.

KW - H-thymidine uptake

KW - cell division

KW - Circadian rhythm

KW - diurnal fluctuations

KW - DNA content

KW - DNA synthesis

KW - exogenous stimulus

KW - frog metabolism

KW - growth

KW - lighting régime

KW - Rana pipiens

KW - rhythms

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U2 - 10.1016/0300-9629(71)90126-5

DO - 10.1016/0300-9629(71)90126-5

M3 - Article

C2 - 4396828

AN - SCOPUS:0015029230

VL - 38

SP - 591

EP - 602

JO - Comparative Biochemistry and Physiology -- Part A: Physiology

JF - Comparative Biochemistry and Physiology -- Part A: Physiology

SN - 0300-9629

IS - 3

ER -

Diurnal fluctuation in dna content and DNA synthesis in the dorsal epidermis of Rana pipiens

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