Dismounting the MDR horse

Edward Libby; Robert Hromas

doi:10.1182/blood-2010-09-304311

Dismounting the MDR horse

Edward Libby
, Robert Hromas

Producción científica: Comment/debate › revisión exhaustiva

45 Citas (Scopus)

Resumen

P-gp (also termed MDR1, or multidrug resistance-1) is a member of the membrane ATP cassette family that mediates efflux of several drugs commonly used to treat AML. Its expression has been correlated with an adverse outcome, ¹ which was thought to occur because it mediates resistance to chemotherapy.

Idioma original	English (US)
Páginas (desde-hasta)	4037-4038
Número de páginas	2
Publicación	Blood
Volumen	116
N.º	20
DOI	https://doi.org/10.1182/blood-2010-09-304311
Estado	Published - nov 18 2010
Publicado de forma externa	Sí

ASJC Scopus subject areas

Hematology
Biochemistry
Cell Biology
Immunology

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title = "Dismounting the MDR horse",

abstract = "P-gp (also termed MDR1, or multidrug resistance-1) is a member of the membrane ATP cassette family that mediates efflux of several drugs commonly used to treat AML. Its expression has been correlated with an adverse outcome, 1 which was thought to occur because it mediates resistance to chemotherapy.",

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language = "English (US)",

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AU - Libby, Edward

AU - Hromas, Robert

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U2 - 10.1182/blood-2010-09-304311

DO - 10.1182/blood-2010-09-304311

M3 - Comment/debate

C2 - 21088139

AN - SCOPUS:78549276901

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JO - Blood

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Dismounting the MDR horse

Resumen

ASJC Scopus subject areas

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