Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus

Jason W. Bennett; Clinton K. Murray; Robert L. Holmes; Jan E. Patterson; James H. Jorgensen

doi:10.1016/j.diagmicrobio.2007.11.002

Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus

Jason W. Bennett
, Clinton K. Murray
, Robert L. Holmes
, Jan E. Patterson
, James H. Jorgensen

Department of Pathology

Producción científica: Article › revisión exhaustiva

25 Citas (Scopus)

Resumen

An elderly patient with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia was treated sequentially with vancomycin plus rifampin then daptomycin plus gentamicin. The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy.

Idioma original	English (US)
Páginas (desde-hasta)	437-440
Número de páginas	4
Publicación	Diagnostic Microbiology and Infectious Disease
Volumen	60
N.º	4
DOI	https://doi.org/10.1016/j.diagmicrobio.2007.11.002
Estado	Published - abr 2008

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1016/j.diagmicrobio.2007.11.002

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title = "Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus",

abstract = "An elderly patient with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia was treated sequentially with vancomycin plus rifampin then daptomycin plus gentamicin. The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy.",

keywords = "Bactericidal effect, Daptomycin resistance, MRSA bacteremia, Minimum inhibitory concentration, Vancomycin tolerance",

author = "Bennett, \{Jason W.\} and Murray, \{Clinton K.\} and Holmes, \{Robert L.\} and Patterson, \{Jan E.\} and Jorgensen, \{James H.\}",

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language = "English (US)",

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AU - Bennett, Jason W.

AU - Murray, Clinton K.

AU - Holmes, Robert L.

AU - Patterson, Jan E.

AU - Jorgensen, James H.

PY - 2008/4

Y1 - 2008/4

N2 - An elderly patient with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia was treated sequentially with vancomycin plus rifampin then daptomycin plus gentamicin. The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy.

AB - An elderly patient with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia was treated sequentially with vancomycin plus rifampin then daptomycin plus gentamicin. The MRSA strain developed diminished susceptibility to vancomycin (MIC increase and tolerance), daptomycin, and gentamicin, and resistance to rifampin during therapy.

KW - Bactericidal effect

KW - Daptomycin resistance

KW - MRSA bacteremia

KW - Minimum inhibitory concentration

KW - Vancomycin tolerance

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JF - Diagnostic Microbiology and Infectious Disease

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Diminished vancomycin and daptomycin susceptibility during prolonged bacteremia with methicillin-resistant Staphylococcus aureus

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