@inproceedings{a4afcc48c50e4edaac50c86af3960c92,
title = "Detection and noninvasive diagnostics of breast cancer with two-color laser optoacoustic imaging system",
abstract = "We have designed, fabricated and tested a new laser optoacoustic imaging system (LOIS-64/16) for quantitative optoacoustic tomography of breast cancer. The system was designed to create a single slice of an optoacoustic image of the breast with 64 ultrawide band acoustic transducers. Other 16 transducers on the back of the acoustic probe were used to reconstruct the light distribution inside the breast. The system resolution was at least 0.5 mm for high-aspect-ratio objects. Maximum system sensitivity was 4.8 mV/Pa and the RMS noise of 3.1 mV, which allowed imaging of small (less than 1 cm) tumors at depths over 3 cm. The directivity of the optoacoustic transducers used in LOIS-64/16 assured that the signal detection was better than 70% of the maximum for about 75% of the imaging slice and reduced quickly for signals coming from out of the imaging slice. Implemented signal processing allowed significant reduction of the low-frequency acoustic noise and localizing the small OA signals. The system was able to differentiate phantoms mimicking tumors and malformations visualized in clinics based on the contrast and morphology of their images obtained at 1064 nm and 757 nm.",
keywords = "Breast cancer, Image reconstruction, Optoacoustic tomography, Optoacoustic transducer array, Quantitative optoacoustic imaging",
author = "Sergey Ermilov and Alan Stein and Andre Conjusteau and Reda Gharieb and Ron Lacewell and Tom Miller and Scott Thompson and Pamela Otto and Mccorvey, {Barbara M} and Tuenchit Khamapirad and Morton Leonard and Alexander Oraevsky",
year = "2007",
doi = "10.1117/12.714039",
language = "English (US)",
isbn = "081946550X",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Photons Plus Ultrasound",
note = "Photons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics ; Conference date: 21-01-2007 Through 24-01-2007",
}