Degradation of MEPE, DMP1, and release of SIBLING ASARM-peptides (minhibins): ASARM-Peptide(s) are directly responsible for defective mineralization in HYP

Biochemistry, Genetics and Molecular Biology

• Peptide 100%
• Serine 73%
• MEPE 68%
• Rickets 47%
• Mineralization 26%
• Wild Type 26%
• Matrix Protein 21%
• PHEX 21%
• Dentin 21%
• Degradation 15%
• Protein 15%
• Nested Gene 10%
• Osteoblast 10%
• Ligand Binding 10%
• Neutralizing Antibody 10%
• Coculture 10%
• Western Blot 5%
• Mutation 5%
• Autosomal Recessive Inheritance 5%
• Osteoclastogenesis 5%
• Osteoclast 5%
• X Chromosome 5%
• Stromal Cell 5%
• Magnetism 5%
• Bone 5%
• Messenger RNA 5%
• Phosphate 5%
• Antibody 5%
• Endopeptidase 5%
• Protease 5%
• Surface Plasmon Resonance 5%