Deep vein thrombosis in anti cardio lipin antibody positive woman: A case report

Anti-phospholipid syndrome (APS) is an autoimmune disease with many different presentations including thrombosis and pregnancy loss. Number of antibodies are implicated in its pathogenesis most importantly antibodies against beta 2- glycoprotein I (B2-GP I). In small subset of patients with deep vein thrombosis (DVT), secondary to APS, anti cardiolipin antibodies are positive. We describe a rare case like this of APS in Pakistani woman who presented with DVT, was treated with warfarin and low molecular weight heparin in hospital and discharged on warfarin with continued follow-up. Physicians should be acutely aware of different presentations of APS and its treatment. The patient we describe has history of multiple still births but APS was only diagnosed later on when she presented to us with DVT.