Craniofacial Disorders Affecting the Dentition: Genetic

Yong Hee P. Chun, Paul H. Krebsbach, James P. Simmer

Producción científica: Chapter


Changes in the dentition and its supporting oral structures may occur in response to disorders of mineral metabolism. This chapter provides a concise overview of the dental manifestations of selected disorders of bone and mineral metabolism, including genetic disorders affecting the number of teeth, dentin, and enamel. The initiation of tooth development depends on interactions between oral epithelium and mesenchyme derived from cranial neural crest cells. Cleft lip and/or palate are relatively common craniofacial malformations that can have profound impact on nutritional, speech, dental, and psychological development. Metabolic diseases of bone are disorders of bone remodeling that characteristically involve the entire skeleton and are often manifest in the oral cavity, which can lead to the diagnosis of the underlying systemic disease.

Idioma originalEnglish (US)
Título de la publicación alojadaPrimer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
Subtítulo de la publicación alojadaEighth Edition
Número de páginas8
ISBN (versión digital)9781118453926
ISBN (versión impresa)9781118453889
EstadoPublished - jul 19 2013

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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