Cortical sulci and bipolar disorder

Thomas R. Coyle, Peter Kochunov, Rupal D. Patel, Fabiano G. Nery, Jack L Lancaster, Jean François Mangin, Denis Rivière, David R. Pillow, Gregory J. Davis, Mark A. Nicoletti, E. Serap Monkul, Peter T. Fox, Jair C. Soares

Producción científica: Articlerevisión exhaustiva

15 Citas (Scopus)

Resumen

The width of cortical sulci in bipolar patients (n=19) and healthy controls (n=35) was examined using a novel automated technique involving magnetic resonance imaging. All sulci were wider for bipolar patients than for healthy controls. Bipolar-control differences were largest for the superior and intermediate frontal sulci, smallest for the occipital and cingulate sulci, and intermediate in magnitude for the other sulci (intraparietal, inferior frontal, and central sulci). The results were interpreted in terms of neurodegenerative-illness-related processes, which could produce cortical atrophy and result in wider sulci.

Idioma originalEnglish (US)
Páginas (desde-hasta)1739-1742
Número de páginas4
PublicaciónNeuroReport
Volumen17
N.º16
DOI
EstadoPublished - nov 2006

ASJC Scopus subject areas

  • General Neuroscience

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