TY - CHAP
T1 - Corneal Dystrophies
AU - Latifi, Golshan
N1 - Publisher Copyright:
© Springer-Verlag London Ltd., part of Springer Nature 2022.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Corneal dystrophies are a group of inherited, usually bilateral, symmetric, slowly progressive disorders affecting the cornea. Traditionally corneal dystrophies have been classified based on anatomic level of involvement, but due to the limitation of this classification, a modified classification is proposed by International Classification of Corneal Dystrophies (IC3D) classification in 2015 (Weiss et al. Cornea. 2015;34(2):117-59). According to the latest revision of IC3D, corneal dystrophies are now divided into (1) epithelial and subepithelial dystrophies, (2) epithelial-stromal TGFBI dystrophies, (3) stromal dystrophies, and (4) endothelial dystrophies. In vivo confocal microscopy (IVCM) offers a non-invasive, high-resolution imaging modality of the living cornea at the cellular level. It helps in diagnosis and understanding the pathophysiology of corneal dystrophies by evaluating the extent and depth of dystrophic depositions and morphological changes of corneal structures at the histological level.
AB - Corneal dystrophies are a group of inherited, usually bilateral, symmetric, slowly progressive disorders affecting the cornea. Traditionally corneal dystrophies have been classified based on anatomic level of involvement, but due to the limitation of this classification, a modified classification is proposed by International Classification of Corneal Dystrophies (IC3D) classification in 2015 (Weiss et al. Cornea. 2015;34(2):117-59). According to the latest revision of IC3D, corneal dystrophies are now divided into (1) epithelial and subepithelial dystrophies, (2) epithelial-stromal TGFBI dystrophies, (3) stromal dystrophies, and (4) endothelial dystrophies. In vivo confocal microscopy (IVCM) offers a non-invasive, high-resolution imaging modality of the living cornea at the cellular level. It helps in diagnosis and understanding the pathophysiology of corneal dystrophies by evaluating the extent and depth of dystrophic depositions and morphological changes of corneal structures at the histological level.
KW - Congenital stromal corneal dystrophy
KW - Corneal dystrophy
KW - Epithelial basement membrane dystrophy
KW - Fuchs’ endothelial corneal dystrophy
KW - Gelatinous drop-like corneal dystrophy
KW - Granular corneal dystrophy
KW - In vivo confocal microscopy
KW - Lattice corneal dystrophy
KW - Macular corneal dystrophy
KW - Meesmann corneal dystrophy
KW - Posterior polymorphous corneal dystrophy
KW - Reis-Bücklers corneal dystrophy
KW - Schnyder corneal dystrophy
KW - Thiel-Behnke corneal dystrophy
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U2 - 10.1007/978-1-4471-7517-9_4
DO - 10.1007/978-1-4471-7517-9_4
M3 - Chapter
AN - SCOPUS:85153838307
SN - 9781447175162
SP - 61
EP - 89
BT - In Vivo Confocal Microscopy in Eye Disease
PB - Springer London
ER -